Organic Selenium as Selenomethionine

Contents: Bulk selenium as organic selenomethionine dietary supplement manufacturers concentrate. Available in bulk powder and now in our new bulk pre-filled capsule packaging for dietary supplement manufacturers and private label applications

Selected yeast strains incorporate selenium in the form of selenomethionine and thus are excellent sources of this natural organic food form of selenium.

Food and Dietary Supplement Manufacturers Concentrated Ingredient  

 Dietary Supplement Information 

Activity Analysis: FG / USP Grade    

Standardized at 2000 mcg/per gram/min

Candida Albicans.........Negative (Verified by DNA Fingerprinting)
E. coli..................................................................Negative
Staphylococcus aureus...........................................Negative

Packaging: Bulk
Ingredient Active Ingredients Se
Selenium (as Selenomethionine) 2000 mcg/g or 2000 ppm
Other Ingredients: Saccharomyces cerevisiae brewers yeast medium

Available in 2 kg and 10 kg bulk containers


Selenium Research  Research Ref. Educational Information 

Yeasts (of Saccharomyces cerevisiae) are widely used in Beer and Wine Brewing, Baking of foods such as bread and cookies and in Feeding of humans and animals. It is very important to emphasize that yeast are able to naturally metabolize inorganic minerals into organic forms, similar to what plants do. Plants do the conversion for us taking the minerals from the soil. Mineral enriched yeast do this by taking the minerals from enriched molasses providing one of the best natural food forms of minerals human can consume. Furthermore, yeast have an excellent storage mechanism for B-vitamins, as do other organisms, for factors needed for growth and life. Yeast is a naturally rich source of proteins, minerals and B-complex vitamins. Not only does mineral enriched yeast offer a natural form of mineral, it also provides other nutrients when consumed.


As the use of nutritional supplements increase, there is a growing consumer demand for more sophisticated information on the products they are consuming. Some of the questions on Selenium Yeast concern the importance of selenium in the diet, the bioavailability of organic Selenium Yeast versus inorganic sources, cancer reduction capabilities of selenium yeast and toxicity issues. We hope that this information will be useful to those considering using selenium supplements. Selenium enriched yeast is the natural, convenient, sate and economical way to increase selenium intake.


Selenium is an essential mineral in human nutrition. Selenium Yeast is a natural dietary selenium supplement with clinically proven physiological value in improving the selenium status in man.

Selenium is a known anti oxidant and is an essential component of Glutathione peroxidase enzyme, which inactivates tree radicals.

Selenium is required in thyroid metabolism while converting active thyroid hormone (14) into the inactive thyroid hormone (13).

lnactivates heavy metals, especially mercury, lead and cadmium.

Selenium Yeast is reported to protect against radiation damage, even it given after exposure.

A maternal selenium intake of 500-750 micrograms in the form of Selenium Yeast is a safe daily intake, adequate for infant and maternal needs. This is based on a study on selenium status of exclusively breast fed infants as influenced by maternal organic (Selenium Yeast) or non-organic (selenite) supplementation in 200 lactating women in Finland.


Nutritecks Selenium Yeast, grown under a carefully monitored fermentation process, binds the selenium into the same organic compounds as found in natural foods.

Several studies have shown that organic selenium such as high Selenium Yeast is more bioavailable than inorganic sources of selenium such as selenate or selenite.

In a study with Finnish men, selenium blood levels of subjects given organic forms (wheat and yeast) of selenium increased up to 10 weeks whereas in the selenate group, selenium blood levels plateaued at a lower levels after 4 weeks (Levander, et al. 1983). In addition, the study also showed that organic forms of selenium were stored in the body and then used at a later time.

A study of selenium supplementation in breast feeding mothers and infants clearly showed that Selenium Yeast was safe and more effective than inorganic selenite in increasing selenium concentrations of maternal blood serum and milk and infant serum (Kumpulainen et. al., 1985).

A Danish study of selenium supplementation in humans, illustrated that organic selenium is more bioavailable than selenate and selenite (Clausen and Nielsen, 1988). Organic selenium compounds, selenomethionine and high Selenium Yeast gave significantly higher blood serum levels and glutathione peroxidase activities than either selenate or selenite.


Selenium Yeast provides a natural protection against several kinds of cancer. Some recent studies have indicated that Selenium Yeast can reduce the incidence of some cancers.

Large scale studies with nutritional supplementation of micronutrients such as selenium have been carried out in China. Selenium Yeast in combination with beta carotene and vitamin F showed that it might reduce the risk of stomach cancer (Blot, a al., 1993). A trial using inorganic selenium and a mixture of 26 micronutrients did not detect any reduction on the incidence or mortality for this type of cancer (Li, et. al., 1993).

A recent study showed that Selenium Yeast had a significant effect on cancer (Clark, et. al. 1996). The large scale American study showed that patients treated with Selenium Yeast had a significant reduction in total cancer mortality, total cancer incidences and incidences of lung, colorectal and prostrate cancers.


The "safe and adequate range" for selenium consumption, established by the US. Food and Nutrition Board, has been set at 50 to 200 mcg/day.

Natural selenium that humans consume is in the form of organic seleno-proteins such as seleno-methionine and seleno-cysteine. Foods such " as fish and whole grain cereals are especially rich in organic selenium compounds (Schrauzer and White 1978).

Selenium Yeast contains high levels of seleno-methionine. It has been estimated that up to700/1000of the selenium in Selenium Yeast is in the form of seleno-methionine.

Evaluations of toxicity of different forms of selenium have shown that high Selenium Yeast is less toxic than inorganic forms of selenium such as sodium selenate and selenite.

A study with rats showed that high doses (1.5 and 3.0 mg/kg body weight) of organic selenium in Selenium Yeast did not have any toxic effects after 14 days. This level of selenium is much higher than the theoretical toxic level for inorganic selenium (Leiras, internal report).

A comparison of the toxicity of a selenite and a Selenium Yeast diet in rats showed that Selenium Yeast was much less toxic (Spallholz and Raftery 1987). No hepatotoxicity, cardiotoxicity or splenomegaly to 16 ppm dietary Se was observed in rats fed high Selenium Yeast over an 8 week period. Animals fed selenite at the same level showed signs of various toxicities.


Selenite and selenate are inorganic chemicals. Simple blends of these with yeast do not make organically bound selenium. One should request the selenomethionine analysis of each lot to ensure that the effective nutritional form of selenium is present.


Selenium is an essential trace element which occurs in cereals and primarily in the form of selenomethionine. This naturally occurring amino acid is the most important food form of selenium.

Selenomethionine is well absorbed and retained. From selenomethionine, all other needed selenium compounds are produced in the body. On the other hand, selenomethionine, like its sulfur analog, methionine, cannot be synthesized efficiently in the human organism.

All quality nutritional selenium supplements should therefore contain selenomethionine

Selected yeast strains incorporate selenium in the form of selenomethionine and thus are excellent sources of this natural organic food form of selenium.

However, low-grade selenium yeasts containing little or no selenomethionine are also marketed. These yeasts are often claimed to contain organically bound" selenium when in fact their selenium is inorganic!

Inorganic selenium compounds are not normal food forms of selenium; they are less well absorbed and retained.

Quality of selenium yeasts contain virtually all of the selenium in the form of selenomethionine.

When ordering Selenium Yeast, make sure to request analytical certification as to its selenomethionine content for each batch.


Blot, 1993 Nutrition intervention trials in Linxian China:

Supplementation with specific vitamin/ mineral combinations, cancer incidence and disease-specific mortality in the general population. J. Natl. Clin. Inst. 85 1483- 1492.

Leiras. Single dose toxicity of selenium yeast. Internal report # 64013-8530.

Borglund, M and Akesson, B. 1988 Effect of selenium supplementation on the distribution of selenium in plasma proteins of health subjects. lnternat. J. Vit. Nutr. Res. 58, 97-102.

Clark, L C. et. al., 1996 Effects of selenium supplementation cancer prevention in patients with carcinoma of the skin. iouri American Medical Assoc. 276 (24), 1957-1963.

Clausen, J. and Nielsen, S. A. 1998 Comparison of whole blood se nium values and erythrocytes of glutathione peroxidase activities normal individuals on supplementation with selenate, seleni L-selenomethionine and high selenium yeast. Biol. Trace EIem. R15, 125-138.

Kumpulainen, i., Salmenpera, L, Siimes, M.A., Koivistoinen, P., a Perheentupa, i. 1985 Selenium status of exclusively breast-I infants as influences by maternal organic or inorganic selenium si plementation. i. Amer. Clin. Nutr. 42, 829-835.

Levander, O.A., Alfthan, G., Arvilommi, H., Gref C.G., Huttunen, i Kataja, M. Koivistoinen, P. and Pikkarainen, i. 1983 Bioavailability selenium to Finnish men as assessed by platelet glutathic peroxidase activity and other blood parameters. Amer. Soc. CIin N37, 887-897.

Li., et. al., 1993 Nutrition intervention trials in Linxian China Multiple vitamin/ mineral supplementation, cancer incidence, disease-specific mortality among adults with esophageal dyspla i. Natl. Clin Inst. 85, 1492- 1498.

Schrauzer, G.N. and White D. A. 1978 Selenium in human nutritition dietary intakes and effects of supplementation. Bioorgan. Chem 303-318.

Spallholz, i. E. and Raftery, A. 1987 Nutritional, chemical toxicological evaluation of high selenium yeast. In The International Symposium of Se in Biology and Medicine 516- 52


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